描述
AlbumiNZ™低内毒素牛血清白蛋白由新西兰来源牛血浆通过符合ISO质量体系的色谱纯化工艺纯化获得，确保完整的可溯性和始终如一的高质量，具有极低的内毒素含量和极低的IgG水平，可简化下游纯化。按照9CFR（《美国联邦法规汇编》第9卷）要求进行无病毒检测，达到极高的生物安全水平。该款BSA可支持干细胞的生长并增加杂交瘤细胞的蛋白产量。
产品特点
- 利用色谱层析法纯化得到
- 血源可自主控制
- ISO9001：2008和cGMP认证
- 单批次产量可达240kg
- 认证的供应链
- 可提供液体或粉末包装形式
产品优势
- 高细胞滴度
- 不同批次的高一致性
- 完全的可追踪性
- 高生物安全性
- 产品质量认证
- 无变性蛋白
应用说明
白蛋白蛋白水、钙离子、钠离子和钾离子。有机结合基团的存在，白蛋白结合聚合物，胆红，有害和药物。白蛋白的主要生物学功能是调节血液的胶体渗透，并压在旁边提供细胞营养。牛白蛋白中含有16%的蛋白质，常被线路背景研究的标准。生态剂。
使用声明
除非另有说明，MP Biomedical 的产品仅供研究或进一步制造使用，不能直接供人类使用。如需更多信息，请联系我们的客户服务部门。
关键应用
干细胞研究| 细胞培养应用 | 免疫测定
| Background_information | Albumins are a group of acidic proteins which occur in the body fluids and tissues of mammals and in some plant seeds. Serum and plasma albumin is carbohydrate-free and comprises 55-62% of the protein present. However, only about 40% of the total albumin in the body is in the circulating plasma at one time with the remainder being in extracellular spaces with which there is, in general, equilibration about every 24 hours. |
| Base Catalog Number | 199896 |
| Biochemical Physiological Actions | Albumin loses its helical structure rapidly in 2-4 M urea and 4 M guanidinium chloride. The unfolding is reversible, even, to some extent, after concomitant reduction of all disulfide bonds . Reduced albumin can reform into structures capable of binding antibodies and other ligands . Formation of SS bonds is rapid but the return of native structure is slow and some wrong disulfide pairings may persist . After oxidation of the cystine bridges, however, native structure is irreversibly lost. |
| CAS # | 9048-46-8 |
| Concentration | Total Protein: ≥95% |
| EC Number | 232-936-2 |
| Format | Lyophilized powder |
| Grade | Cell Culture Grade, ImmunoAssay (EIA) Grade |
| Host | Bovine |
| Molecular Weight | 66KDa |
| pH | 6.5 – 7.5 (4% aq soln) |
| Purity | ≥97% Total Protein |
| Solubility | Albumins are readily soluble in water and can only be precipitated by high concentrations of neutral salts such as ammonium sulfate. The solution stability of albumin is very good (especially if the solutions are stored aliquoted and frozen). Albumin is readily coagulated by heat. When heated to 50 °C or above, albumin quite rapidly forms hydrophobic aggregates which do not revert to monomers upon cooling. Dissolves completely in 20 min at 20-25 °C (20%). |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
